Gut Power: How Your Microbiome Shapes Longevity

Dr. Derrick DeSilva explores how the gut microbiome influences aging by shaping immune function, digestion, vitamin production and neurotransmitter levels. He reviews research showing centenarians harbor unique bacteria that produce protective secondary bile acids and discusses how those compounds can slow harmful infections.

The episode highlights the role of butyrate-producing bacteria (e.g., Faecalibacterium prausnitzii) in reducing inflammation, supporting mitochondrial function, protecting telomeres and promoting cellular cleanup, all linked to healthier aging.

Practical takeaways include using effective probiotics, optimizing nutrients (vitamin D, A, K, methylated B complex), considering genetics and lifestyle changes.